253.3 📌 章末速蚘

253.3.0.0.1 CDC Categories
  • A: anthrax, smallpox, plague, botulism, tularemia, VHF
  • B: brucellosis, glanders, Q fever, ricin
  • C: emerging — nipah, MDR-TB
253.3.0.0.2 Anthrax
  • Cutaneous painless black eschar; inhalational widened mediastinum; cipro/doxy × 60 days + antitoxin
253.3.0.0.3 Smallpox
  • Eradicated 1980; bioterror; synchronous lesions; ACAM2000 + JYNNEOS vaccines; tecovirimat
253.3.0.0.4 Plague
  • Bubonic + septicemic + pneumonic; streptomycin or gent; isolation pneumonic
253.3.0.0.5 Botulism
  • Descending flaccid paralysis + 4 D’s; BAT antitoxin + ventilation
253.3.0.0.6 Tularemia
  • F. tularensis; streptomycin or gent; PEP: doxy/cipro × 14 d
253.3.0.0.7 VHF
  • Ebola + Marburg + Lassa + Junín; supportive + ribavirin (Lassa) + mAbs (Ebola); vaccines
253.3.0.0.8 Response
  • Recognize → notify → isolate → PPE → BSL-3+ → empirical Tx → PEP → mass casualty → forensic
253.3.0.0.9 盧醫垫 hint
  • Sudden multiple inhalational anthrax cases / unexplained mediastinitis cluster → bioterror response
  • Pneumonic plague suspected → isolation + streptomycin + PEP for contacts
  • Bioterror = public health emergency; rapid recognition saves lives