251 Ch 251. Pneumocystis jirovecii Pneumonia (PJP)

Opportunistic fungus (reclassified from protozoan); HIV CD4 < 200, transplant + corticosteroids + chemo + anti-CD20 = major risk; TMP-SMX first-line + steroid if A-a > 35 or PaO2 < 70; β-D-glucan elevated; insidious dry cough + dyspnea + hypoxia + bilateral interstitial CXR。