296 Ch 295. Cardiac Involvement in Systemic Diseases

系統性疾病心臟侵犯 是 internal medicine 的重要交叉領域；autoimmune / CTD：SLE (libman-sacks endocarditis, pericarditis, myocarditis)、RA (pericarditis, accelerated atherosclerosis)、systemic sclerosis (myocardial fibrosis, PAH)、APS (thrombosis, valve abnormalities)、Sjögren、PM/DM；vasculitis affecting heart：Takayasu (large vessel, aortitis, coronary ostia)、GCA、PAN、ANCA-associated (eosinophilic granulomatosis = Churg-Strauss with myocarditis)；infiltrative：amyloidosis (AL, ATTR-wild type, ATTR-hereditary)、sarcoidosis、hemochromatosis、Fabry、Gaucher、glycogen storage；endocrine：thyroid (hyper/hypo)、acromegaly、Cushing、pheo、diabetes (cardiomyopathy + CAD)、hyperparathyroidism；infectious：syphilis (aortitis)、TB (constrictive pericarditis)、HIV、Chagas、Lyme；hematologic：sickle cell (PH, cardiomyopathy)、thalassemia (iron overload)、MPN；genetic / neuromuscular：Marfan、Loeys-Dietz、vEDS、Friedreich’s ataxia (HCM)、Duchenne (DCM)、myotonic dystrophy (conduction)；HIV + cardiomyopathy + accelerated atherosclerosis；COVID-19 long-term：post-acute sequelae 含 myocarditis、HFpEF-like, autonomic dysfunction。