63.3 🩺 內科專科考前版

63.3.0.1 📌 䞀頁重點

  • 22E: cyclosporine for TEN, etanercept emerging, HLA testing wider
  • Taiwan: HLA-B1502 / B5801 testing 健保郚分

63.3.0.2 🌟 Pearls (8)

  1. Cyclosporine for TEN > IVIG (CHU-Lille 2018)
  2. Etanercept small RCT shows benefit in TEN
  3. DRESS RegiSCAR criteria
  4. HHV-6 PCR in DRESS
  5. Long taper in DRESS (months)
  6. Immune checkpoint inhibitor dermatitis rising
  7. Drug rechallenge absolute contraindication after SJS/TEN/DRESS
  8. HLA Pharmacogenomics 亞掲族矀 carbamazepine B*1502 必驗

63.3.0.3 📍 Taiwan

  • HLA-B*1502 carbamazepine 健保2010+
  • HLA-B*5801 allopurinol testing 掚廣䞭
  • Cyclosporine TEN 自費
  • Immune checkpoint inhibitor 皮膚副䜜甚䞊升

63.3.0.4 🎓 內專重點

  1. 5 類藥疹 time course
  2. HLA pharmacogenomics
  3. TEN treatment evolution
  4. DRESS RegiSCAR + sequelae
  5. Drug rechallenge

⚠ AI 草皿。