217 Ch 217. HIV Antiretroviral Therapy + Clinical Management

“Triple ART era” since 1996; modern STR (single tablet regimen) revolutionized; InSTI-based first-line (dolutegravir, bictegravir); long-acting injectable cabotegravir/rilpivirine (Cabenuva); lenacapavir 2025 every-6-month; PrEP (Truvada, Descovy, cabotegravir injectable, lenacapavir); U=U achievable in well-managed; resistance + drug interactions critical。