65.3 🩺 內科專科考前版

65.3.0.1 📌 䞀頁重點

  • 22E 匷化 smear interpretation in 急症TTP, AML M3 APL
  • AI-augmented hematology imaging emerging
  • Taiwan: thalassemia 高 → target cells / microcytosis 垞芋

65.3.0.2 🌟 Pearls (8)

  1. TTP smear + neuro + 䞍癌燒 → ADAMTS13 + plasma exchange ASAP
  2. APL (M3) Auer rods + DIC → ATRA STAT
  3. CLL smudge cell % correlates with prognosis (lower better)
  4. Rouleaux prompt SPEP
  5. Tear drop with leukoerythroblastic = myelofibrosis vs marrow infiltration
  6. Pelger-Huet acquired = MDS prognostic
  7. Spherocyte AIHA = direct Coombs +
  8. EDTA pseudothrombocytopenia → recheck citrate / heparin tube

65.3.0.3 📍 Taiwan

  • α/β-thalassemia 高 → microcytic target
  • G6PD deficiency 兒童篩檢
  • Splenectomy post-trauma → Howell-Jolly

65.3.0.4 🎓 內專重點

  1. RBC morphology 對應病
  2. WBC abnormality
  3. MAHA causes
  4. APL 緊急
  5. Smear in MDS

⚠ AI 草皿。