182.2 📚 國考版

182.2.0.1 必背 — Three Endemic Treponematoses

• Yaws: tropical, kids, papilloma “mother yaw” → 多 secondary 紅疹 + bone/dactylitis → late gummas + gangosa
• Bejel (Endemic syphilis): dry W Africa/Middle East, oral, kids, palate destruction
• Pinta: C/S America, skin, depigmentation late

182.2.0.2 必背 — Distinct from Syphilis

• Non-sexual transmission (skin-skin, oral)
• No CV / neuro involvement
• Same Treponema family — serology indistinguishable
• Children primary affected

182.2.0.3 必背 — Treatment

• Azithromycin 30 mg/kg PO × 1 (WHO preferred)
• Benzathine PCN G 1.2-2.4 M IM × 1 alt

182.2.0.4 必背 — WHO Yaws Eradication 2030

• Mass azithromycin TCT/TTT strategies
• India eradicated 2016, Ecuador 2024
• Single-dose azithromycin breakthrough vs old PCN-IM logistic

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