60.2 📚 國考版醫垫國考 / PGY OSCE

60.2.0.1 📌 Cram Sheet

60.2.0.1.1 🔥 高 yield 12
  1. AD 䞉聯asthma + 錻炎 + ADatopy march
  2. AD 屈偎 / Psoriasis 䌞偎
  3. Auspitz sign = psoriasis
  4. Koebner = psoriasis, lichen planus, vitiligo
  5. Dupilumab for ADanti-IL-4Rα
  6. IL-17 / IL-23 biologics for psoriasis
  7. Honey-colored crust = impetigo (Staph/Strep)
  8. Erysipelas 邊界枅 vs cellulitis 暡糊
  9. Scabies 倜癢 + burrow → permethrin
  10. Isotretinoin teratogenic — 嚎栌 contraception
  11. Tinea KOH + → topical antifungal
  12. Guttate psoriasis post-strep
60.2.0.1.2 🔢 必背
項目 æ•žå­—
Filaggrin mutation in AD 30%+
PsA in psoriasis 30%
Isotretinoin dose 0.5-1 mg/kg/d × 16-20 週
Cumulative isotretinoin 120-150 mg/kg
Permethrin scabies 5% cream

60.2.0.2 ⭐ 高 yield

60.2.0.2.1 Eczema vs Psoriasis 對照
Eczema Psoriasis
分垃 屈偎 䌞偎 + 頭皮
性質 Itchy, weeping, lichen Plaque, silver scale
Koebner − +
Auspitz − +
Atopy + −
Th 䞻導 Th2 Th17
Biologic Dupilumab (IL-4Rα) IL-17, IL-23, TNF-α
60.2.0.2.2 Biologics for Psoriasis (22E)
Target Drug
TNF-α Adalimumab, etanercept, infliximab
IL-12/23 Ustekinumab
IL-23 Guselkumab, risankizumab, tildrakizumab
IL-17 Secukinumab, ixekizumab, brodalumab
TYK2 (oral) Deucravacitinib (22E new)
60.2.0.2.3 Biologics for AD (22E)
Target Drug
IL-4Rα Dupilumab
IL-13 Tralokinumab, lebrikizumab
JAK Abrocitinib, upadacitinib (oral); ruxolitinib (topical)
60.2.0.2.4 Cutaneous Infection Bacteria
  • Impetigo: Staph aureus, Strep pyogenes
  • Erysipelas: Strep pyogenes (group A)
  • Cellulitis: Staph/Strep
  • Folliculitis: Staph aureus
  • Furuncle/Carbuncle: Staph aureus
60.2.0.2.5 Isotretinoin Caveats
  • Teratogenic懷孕絕犁
  • Pregnancy test 兩次 negative + å…©çš® contraception 1 個月前 + 期間 + 1 個月埌
  • 肝功胜、lipid 監枬
  • Suicidal ideation watch爭議

60.2.0.3 🎯 自我檢枬

  1. AD 䞻導 cytokine? → Th2 (IL-4, 13)
  2. Psoriasis 䞻導? → Th17 (IL-17, 23)
  3. Auspitz sign? → Psoriasis
  4. Koebner 侉病? → Psoriasis, lichen planus, vitiligo
  5. Dupilumab target? → IL-4Rα
  6. Honey-colored crust? → Impetigo
  7. Permethrin? → Scabies
  8. Isotretinoin 副䜜甚? → Teratogenic, cheilitis, hyperlipidemia
  9. Guttate psoriasis trigger? → Strep
  10. Deucravacitinib target? → TYK2 (22E new for psoriasis)

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