235 Ch 235. Free-Living Amebae

3 main human pathogens (Naegleria fowleri — PAM rapid death; Acanthamoeba — GAE + keratitis + cutaneous; Balamuthia mandrillaris — GAE chronic); PAM: warm freshwater swimming, nasal entry → cribriform plate → brain, mortality > 97%; Naegleria + miltefosine + experimental combination rare survivors。